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A semisynthetic antibiotic produced from Streptomyces mediterranei It has a broad antibacterial spectrum including activity against several forms of Mycobacterium In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme It thus suppresses the initiation of RNA synthesis Rifampin is bactericidal and acts on both intracellular

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Molecular Weight 238 712 g mol Molecular Formula C 9 H 19 ClN 2 O 3 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 3 Exact Mass 238 108

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